Supplementary Figure 10: A complex maze for evaluating the control of mouse behavior by MIDAS.
From: Medial preoptic circuit induces hunting-like actions to target objects and prey
a. The maze consists of seven hurdles: ① a zig-zag course; ② a female distractor; ③ blind alleys; ④ rough terrain; ⑤ a mesh ladder; ⑥ food distractors; and ⑦ a bridge. b. Latency to the goal during a 300-s navigation session. Note that the OC+ LC condition showed significantly less latency than the other conditions (n = 5 mice; One Way RM ANOVA, OC only vs. OC+LC, P < 0.001; LC only vs. OC+LC, P < 0.001). c. Frequency of getting trapped in the hurdles, quantified as described in the Methods. Note that mice in the OC+LC condition were trapped in the hurdles significantly less often than mice of the other conditions (n = 5 mice; One Way RM ANOVA, OC only vs. OC+LC, P = 0.009; LC only vs. OC+LC, P = 0.008). Bar graphs indicate mean (bars) ± SEM (error bars) and individual data (circles). See the detailed statistical values in Supplementary table 1. * P < 0.05
