Supplementary Figure 2: Hippocampus-driven IL responses are monosynaptic, time-locked responses. | Nature Neuroscience

Supplementary Figure 2: Hippocampus-driven IL responses are monosynaptic, time-locked responses.

From: Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

Supplementary Figure 2

a, Example of a HPC-driven response in a pyramidal neuron, containing the initial excitatory response, followed by an inhibitory component. The 5-fold enlarged inset shows the time-locked onset of individual responses (grey) to the light stimulation (blue) without any response-failures. Averaged response shown in black. Analysis of EPSCs show very low response jitter (b) (individual jitter of neurons shown as grey dots; n = 19) and response latency (c) (n = 14), both typical parameters for monosynaptic responses. Error bars indicate means ± s.e.m.

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