Supplementary Figure 6: Summary of physiological properties of CA3 pyramidal cells.

a) Representative firing patterns from a regular spiking and a bursting cell where the boxed region indicates an isolated single spike utilized for feature extraction. b) Overlaid individual traces (grey) and average (black, regular spiking (n = 20 cells); red, bursting (n = 14 cells)) of action potential waveforms that are peak aligned. Inset, onset alighted trace averages with bounded SEM error clouds, indicating a more prominent fast after-hyperpolarization potential (fAHP) for regular spiking cells, and a more pronounced after-depolarizing potential (ADP) for bursting cells. c) Phase plot of spike waveform averages for regular spiking (black) and bursting neurons (red) indicating a difference in the rising phase of the action potential waveform between the two cell-types. Inset, upper right (boxed region) illustrates the difference in action potential threshold between the two cell-types. d) Population histograms across all recordings for each feature.