Supplementary Figure 13: Simulating cell-type-specific intrinsic properties with ADEX neuron models.

a) Representative traces of increasing current injection for adaptive integrate-and-fire models tuned to have different intrinsic properties. Two excitatory cell-types are modeled as regular spiking and bursting neurons. One inhibitory cell-type is modeled as fast spiking. b) Initial firing frequency of cell-types described in (a) for a range of somatic current injections, note the steep gain function of the bursting cells (red) compared to that of the regular spiking cells (black). c) Summary of network configurations where the proportion of excitatory to inhibitory neurons is constant but the ratio of regular spiking to bursting neurons is systematically changed. d) Table summarizing the cell-type specific parameters used for the adaptive integrate and fire neurons. For the inhibitory cells, parameters were varied by a random amount (r) sampled from a uniform distribution over the range [0,1].