Supplementary Figure 10: Remission phase mice show normal visual discrimination and rotarod performance.
From: Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis
(a) Schematic illustration of visual discrimination task set-up. (b) Pre-training of EAE mice to perform visual discrimination tasks. No difference observed between healthy controls and mice before EAE induction when pre-training was performed. (c) Time course of the correct choice in visual discrimination task in relation to the clinical EAE score during remission (mean ± SEM; healthy controls n = 10; remission phase animals n = 10). (d) Rotarod behavior task. Latencies (s) until the mice fell off for each group are shown. Box-and-whisker plot indicates the median value (center line), the 25 –75th percentiles (box) and the 10–90th percentiles (whiskers); (two-sided t-test, P = 0.8062; healthy controls n = 9; remission phase animals n = 10).
