Supplementary Figure 6: Calcium imaging of spontaneous activity in pyramidal neurons† in V1 (corresponds to data in Fig. 3). | Nature Neuroscience

Supplementary Figure 6: Calcium imaging of spontaneous activity in pyramidal neurons† in V1 (corresponds to data in Fig. 3).

From: Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible

Supplementary Figure 6

a. There was no significant difference in the amplitude of the calcium signals (as assessed with the mean Z-score of fluorescence) of pyramidal neurons in L2/3 of V1 cortex between WT and Fmr1-/- mice during recordings of spontaneous activity. Unpaired two-tailed Student’s t-test for panels a-b. In both panels horizontal bars indicate the mean and error bars indicate s.e.m. b. There was no significant difference in the frequency of peaks of calcium fluorescence of pyramidal neurons in L2/3 of V1 cortex between WT and Fmr1-/- mice during recordings of spontaneous activity. †In this legend, the term ‘pyramidal’ refers to all cells recorded using GCaMP6s, the vast majority of which are pyramidal neurons.

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