Supplementary Figure 10: No significant effect of hM3Dq and CNO on spontaneous PV cell activity (corresponds to data in Fig. 5a–e). | Nature Neuroscience

Supplementary Figure 10: No significant effect of hM3Dq and CNO on spontaneous PV cell activity (corresponds to data in Fig. 5a–e).

From: Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible

Supplementary Figure 10

a,b. In PV-Cre x Fmr1-/- mice injected with the hM3Dq DREADD virus in V1, CNO injection led to no significant changes in either the overall frequency of calcium transients (as measured by the mean fluorescence Z-scores per s) or the frequency of calcium peaks for PV cells. n = mice, Fmr1-/-, HM3Dq (before and after CNO) (6). Unpaired two-tailed student’s t-test. In both panels horizontal bars indicate the mean and error bars indicate s.e.m.

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