Supplementary Figure 10: Selective silencing of Ca²⁺ spikes affects sensorimotor behavior (part 2).

a, Mean change in whisker angle across all mice (control (black) and perturbed (red). Asterisks indicate statistical significance (two-sample Kolmogorov-Smirnov test) between the groups where p=0.0074 at session 3 and 0.013 at session 5. b, Fraction of false alarms during baseline and switch sessions in the control (black) and active L5 integration perturbed (red) mice. c, Behavioral performance (d’) during baseline and switch sessions in control (black) and perturbed (red) mice showing no drop in detection or choice performance. d, Fraction of reward trials in control and tuft silenced mice. e, Mean fraction of whisker contact trials in control (black) and tuft silenced (red) mice). f, Behavioral performance in a subset of mice (n=4) and the impact of trimming the single (C2) whisker after 6 sessions. Significant drop in performance to chance levels from trimming the C2 whisker shows that task performance was dependent on active C2 whisker contacts alone. In a-e, all symbols are mean±sem.