Supplementary Figure 1: EGFP+ regions in the brain and the spinal cord after PRV injection into the bladder wall. | Nature Neuroscience

Supplementary Figure 1: EGFP+ regions in the brain and the spinal cord after PRV injection into the bladder wall.

From: A corticopontine circuit for initiation of urination

Supplementary Figure 1

a, Reconstructed images (top) and diagrams (bottom) of PRV-EGFP-labeled regions in the mouse brain on the sagittal (left) or coronal plane (right). The PRV-infected brain areas mainly include cerebral cortex (cortex), medial preoptic area (MPA), paraventricular nucleus (PVN), lateral hypothalamic area (LH), red nucleus (Red N), periaqueductal grey (PAG), locus coeruleus (LC), pontine micturition center (PMC), gigantocellular reticular nucleus (Gi), A5 noradrenaline cells (A5) and raphe nuclei. d: dorsal; v- ventral; r: rostral; c: caudal; l: left; ri: right. b, Left, schematic representation of the descending neural pathways infected by PRV. Right, confocal images showing the sections corresponding to the left panel. c-f, Coronal sections showing the lateral hypothalamic area (LH), PAG, red nucleus (Red N), A5 noradrenaline cells (A5), the gigantocellular reticular nucleus (Gi) and the raphe nuclei. All of these experiments were repeated independently in 3 male mice with similar results.

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