Supplementary Figure 6

CD206 expression on human microglia and perivascular macrophages. (a) A dot plot graph shows mean expression levels of P2Y12 in CD206-negative huMG (filled dots) from GTS (blue, n = 8) and GFM (orange, n = 7) compared with CD206hi perivascular macrophage (pmΦ, circles) from GTS (blue, n = 8) and GFM (orange, n = 7). Black lines show the mean of data acquired by mass cytometry (CyTOF). (b) An overlaid histogram plot displays low expression of CD206 in P2Y12+ huMG from GTS (blue) and GFM (orange) showing the high autofluorescent background of postmortem samples analyzed by flow cytometry (FACS). Two experiments were independently repeated with similar results.