Supplementary Figure 10: Optogenetic activation of PVN CRF neurons of food-restricted mice reduces preference for food and for food-paired chamber.
From: Rapid, biphasic CRF neuronal responses encode positive and negative valence
a–e, Time spent in eating normalized to time spent in the food-paired chamber (%) (a), the number of eating bouts (b), the duration of eating bout (c), probability of initiating eating when mice are in the food-paired chamber (%) (d), and cumulative bouts from days 3, 4, and 5 (e) in PVN-CRFChR2 mice (blue, N = 12) and control PVN-CRFeYFP (gray, N = 9) mice. Two-way ANOVA test with Holm–Sidak post hoc analysis. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Data are presented as mean ± s.e.m. Related to Fig. 6.
