Supplementary Figure 5: Concordance between TF motif enrichment analysis and footprint data.

(A-B) Heatmap representing the enrichment (red, one-sided Fisher’s Exact Test multiple comparisons adjusted Pval<0.05) of the 150 top-ranked motifs in the DA regions (TSS+/-1Kb and enhancers), and in the DE genes (TSS+/-1Kb), the footprints calculated by HINT (purple, occupational score), and the relative TF expression level (turquoise, FPKM), after SNA vs sham (A), or DCA vs lam (B). For each TF, the highest occupational score has been reported.