Supplementary Figure 8: Sensorimotor assessments.

CatWalk Automated Gait Analysis (A-F) and Von Frey (G) analysis of CTCF-cKO vs WT mice after SNC. Mice were assessed 1 day before injury, as baseline, and then at the indicated time points after SNC. (A) Run speed (the average speed of the recorded run; mean + s.e.m. of N=9 or 10 mice; 2-way ANOVA, Sidak’s multiple comparison test; ns=not significant; full statistics in Supplementary Data 15); (B) Max Intensity (maximum intensity of the complete paw; mean + s.e.m. of N=6 or 7 mice; 2-way ANOVA, Sidak’s multiple comparison test; ns=not significant; full statistics in Supplementary Data 15); (C) Max Contact Max Intensity (the maximum Intensity at maximum contact of the paw; mean + s.e.m. of N=6 or 7 mice; 2-way ANOVA, Sidak’s multiple comparison test; ns=not significant; full statistics in Supplementary Data 15); (D) Hind paw print width (the width of the complete paw print; mean + s.e.m. of N=6 or 7 mice; 2-way ANOVA, Sidak’s multiple comparison test; ns=not significant; full statistics in Supplementary Data 15); (a.u., aribitrary units); (E) Manual Print Length (the distance between the center of the third toe and the heel of a paw; mean + s.e.m. of N=12-20 prints; 2-way ANOVA, Turkeys’s multiple comparison test; ns=not significant; full statistics in Supplementary Data 15); (F) Intermediate Toe Spread (the distance between the center of the second and fourth toe of a hind paw; mean + s.e.m. of N=6-20 prints, 2-way ANOVA, Turkeys’s multiple comparison test; ns=not significant; full statistics in Supplementary Data 15); (G) The minimum force (g) applied in order to have a positive withdrawal response (mean + s.e.m. of N=9 mice; 2-way ANOVA, Sidak’s multiple comparison test; ns=not significant; full statistics in Supplementary Data 15).