Supplementary Figure 1: Effects of PCE on pregnancy outcome.
From: Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone
(a) Bar graph showing that the size of the litters of CTRL and PCE dams (nlitter= 37 and nlitter= 35, respectively) is similar (P=0.47, ns, t(70)=0.723; two-sided unpaired t-test). (b) Total maternal and (c) non maternal behavior displayed by CTRL and PCE dams (nlitter= 9 and nlitter= 11, respectively) towards the pups over a period of three weeks (P=0.84, ns, F(1,18)=0.043; two-way RM ANOVA). Data are represented as mean ± S.E.M. (d) Bar graph summarizing no differences in the weight of male pups prenatally treated with either vehicle (CTRL, npups= 38, nlitter= 17) or THC (PCE, npups= 34, nlitter=17) at postnatal day 25 (P=0.099, ns, t(70)=1.67; two-sided unpaired t-test). Data in (a,d) are represented as box-and-whiskers plot (including minima, maxima, and media values, and lower and upper quartiles) with single values.
