Extended Data Fig. 1: Non-normalized data for curcumin fluorescence spectral assay.
From: α-Synuclein strains target distinct brain regions and cell types
S fibrils, NS fibrils, or non-polymerized (monomeric) forms of recombinant α-syn(A53T) were subjected to the curcumin dye-binding assay. Spectra were background-corrected but were not normalized. Only the fibrillar forms of α-syn gave appreciable signal, indicating that the assay is specific for aggregates. Each data point represents the mean relative fluorescence obtained from 3 biologically independent fibril preparations ± s.e.m.
