Extended Data Fig. 7: Neuronal activity across trial epochs of the associative memory task.
A) Overhead view of the X-Maze and the subject’s trajectory through the maze on two consecutive trials. Each trial contains five distinct trial epochs. During the Post-reward and Pre-context epochs, all maze walls are grey and no rewarded objects are visible. Once the subject enters the central corridor, the context is cued using a wood or steel material applied to some of the maze walls. Once the subject leaves the corridor for the branched area of the maze, an object is made visible simultaneously in each arm of the maze. Subjects learn a reversed context-object reward value hierarchy by trial and error. B) Spike locations and firing rate by trial epoch for six example neurons during the associative memory task. Left: trajectories through the X-Maze (translucent grey) and spike locations (translucent red). Right: Box plot showing firing rate by trial epoch in the associative memory task. Dots indicate median value; lines indicate the 25th to 75th percentile; outliers are plotted individually. *, p<0.05 compared to the trial epoch with the lowest firing rate; Kruskal-Wallis, Bonferroni-corrected.
