Extended Data Fig. 5: Lipid droplet containing microglia in the cortex, corpus callosum, and thalamus of GRN-/- mice. | Nature Neuroscience

Extended Data Fig. 5: Lipid droplet containing microglia in the cortex, corpus callosum, and thalamus of GRN-/- mice.

From: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

Extended Data Fig. 5

a-c, Representative confocal images of BODIPY+ (lipid droplets) and Iba1+ (microglia) in the cortex (a), corpus callosum (b), (c) and thalamus from 9-month-old male GRN-/- mice. BODIPY+/Iba1+ cells were frequently found in the thalamus and were detected to a lesser extent in cortex and corpus callosum. Data were replicated in at least three independent experiments.

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