Extended Data Fig. 1: Lipid droplet accumulating microglia are abundant in the hippocampus but rare in other brain regions of aged mice. | Nature Neuroscience

Extended Data Fig. 1: Lipid droplet accumulating microglia are abundant in the hippocampus but rare in other brain regions of aged mice.

From: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

Extended Data Fig. 1

a–d, Representative confocal images of the cortex (a), thalamus (b), corpus callosum (c) and hippocampal dentate gyrus (d) from 20-month old male mice stained for BODIPY+ (lipid droplets) and Iba1+ (microglia). Scale bar: 20 μm. Arrows point towards BODIPY+ lipid droplets. e, Quantification of BODIPY+/Iba1+ cells. n = 4 mice per group. One-way ANOVA followed by Tukey’s post hoc test. Error bars represent mean ± SD. ***P< 0.001.

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