Extended Data Fig. 10: Effect of intrathecal injection of NE and phenylephrine at higher doses on mechano- and thermosensory behaviors.

a, b, PWT (a) or PWL (b) in wild-type mice 30 min after intrathecal injection of noradrenaline (n = 6 mice per group; two-tailed paired t test and two-tailed Wilcoxon matched-pairs signed rank test). c, d, PWT (c) or PWL (d) in wild-type mice 30 min after injection of phenylephrine (n = 6 mice per group; two-tailed paired t test). Data show the mean ± s.e.m. See source data for statistical parameters.