Extended Data Fig. 3: Bayesian Decoding of Position in the three-chamber task. | Nature Neuroscience

Extended Data Fig. 3: Bayesian Decoding of Position in the three-chamber task.

From: Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model

Extended Data Fig. 3

a, Bayesian decoding of position based on CA1 activity (dark-shaded bars) in one example animal was significantly greater than chance performance (light-shaded bars) in all five sessions of the three-chamber task. Example shown for one wild-type animal. (*p < 0.05, **p < 0.01, **p < 0.001, two-sided Wilcoxon Rank Sum). b, Example Bayesian decoding of position from CA2 activity in two animals in the three-chamber task. For all 6 wild-type animals examined, the Bayesian decoder for position based on CA2 neuron activity never performed significantly better than chance. (p > 0.05, two-sided Wilcoxon Rank Sum). P values relative to chance for all WT mice with CA2 recordings were equal to: WT7, p = 0.48; WT2, p = 0.36; WT3, p = 0.06; WT5, p = 0.17; WT10, p = 0.19; WT9, p = 0.49. Box plots display the center line as the mean; box limits are upper and lower quartiles; whiskers show min to max values in data sets. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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