Extended Data Fig. 7: Cross-dataset TWAS analyses. | Nature Neuroscience

Extended Data Fig. 7: Cross-dataset TWAS analyses.

From: Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk

Extended Data Fig. 7

a, TWAS Z scores across three datasets are highly correlated. Correlations were highest between DLPFC and HIPPO (ρ = 0.64), followed by DG-GCL and HIPPO (ρ = 0.53) then DG-GCL and DLPFC (ρ = 0.50). Overlap of TWAS gene-level associations across three datasets at b, FDR < 5% significance and c, Bonferroni < 10% significance.

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