Extended Data Fig. 8: Case-control differential expression analyses. | Nature Neuroscience

Extended Data Fig. 8: Case-control differential expression analyses.

From: Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk

Extended Data Fig. 8

a, Comparisons of log2 fold change effect sizes across diagnoses in the DG-GCL dataset. Comparison of the schizophrenia b, log2 fold changes and c, T-statistics for DG-GCL versus bulk Hippocampus. Color indicates FDR < 0.05 significance indicated in the legend. d, TWAS versus differential expression for schizophrenia effects among 12256 expressed genes with positive heritability (N = 12256) shows no association.

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