Extended Data Fig. 4: RI behavior in NONs during optogenetic stimulation of OxR2 over-expression in LHb GAD2 neurons.
From: Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice
a, ChR2-mediated stimulation of GAD2 LHb neurons in NONs did not affect attack latency during RI (two-tailed paired t-test, n = 7 biologically independent mice, t(6)=1.0, p = 0.3559). b, ChR2-mediated stimulation of GAD2 LHb neurons in NONs did not affect attack duration during RI (two-tailed paired t-test, n = 7 biologically independent mice, t(6)=1.0, p = 0.3559). c, ChR2-mediated stimulation of orexin terminals in the LHb did not affect attack latency during RI (two-tailed paired t-test, n = 6 biologically independent mice, t(5)=1.0, p = 0.3632). d, ChR2-mediated stimulation of orexin terminals in the LHb did not affect attack duration during RI (two-tailed paired t-test, n = 5 biologically independent mice, t(5)=1.0, p = 0.3632). e, Over-expression of OxR2 in GAD2 LHb neurons in NONs did not affect attack latency during RI (two-tailed student’s t-test, n = 8 biologically independent GFP mice and n = 11 biologically independent OxR2-OE mice, t(17)=0.8338, p = 0.4160). f, Over-expression of OxR2 in GAD2 LHb neurons in NONs did not affect attack duration during RI (two-tailed student’s t-test, n = 8 biologically independent GFP mice and n = 11 biologically independent OxR2-OE mice, t(17)=0.9951. All data are expressed as mean ± SEM.
