Extended Data Fig. 7: Comparison to adult dorsolateral prefrontal cortex (DLPFC) caQTLs. | Nature Neuroscience

Extended Data Fig. 7: Comparison to adult dorsolateral prefrontal cortex (DLPFC) caQTLs.

From: Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation

Extended Data Fig. 7

a, Shared accessible peaks overlap at epigenetically annotated regulatory elements from different tissues. Accessible peak bp percentage overlapped with epigenetically annotated regulatory elements. From left to right, tissues ordered by bp percentage overlap with enhancers and promoters. Shared peaks overlap with both adult and fetal regulatory elements. b, PCA plot for read counts from shared peaks in adult DLPFC, neurons and progenitors. c, Correlations of effect sizes for significant neuron caQTLs and the same SNP-Peak pairs in adult DLPFC (left). Correlations of effect sizes for significant progenitor caQTLs and the same SNP-Peak pairs in adult DLPFC (right).

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