Extended Data Fig. 9: DCX protein expression levels 1 month post PTB-ASO treatment in human organoid cultures. | Nature Neuroscience

Extended Data Fig. 9: DCX protein expression levels 1 month post PTB-ASO treatment in human organoid cultures.

From: Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB

Extended Data Fig. 9

a, Representative images of a 5-month-old human organoid taken a 1-month post PTB or control ASO treatment. (Green) DCX visualized by immunofluorescence; (blue) DAPI to stain DNA; experiment was reproduced four times, independently, with similar results. b, Total DCX area in either PTB-ASO or control treated organoids. Data are presented as fold change mean +/− s.e.m. (control: 1 +/− 0.09; PTB-ASO mean: 1.43 +/− 0.13; n = 4 biological repeats, two tailed t test *p = 0.042).

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