Extended Data Fig. 2: Effects of V2M, M2, and S1 inactivation on task performance.
From: Gated feedforward inhibition in the frontal cortex releases goal-directed action
a, Schematic of MUS injection (top) and histological confirmation of MUS injection (bottom) into the V2M (a1), M2 (a2), and S1 (a3). Scale bars, 1 mm. b, Example lick raster plots of mice at each injection condition (V2M MUS (b1), M2 MUS (b2), and S1 MUS (b3)). gray shade, visual stimuli; blue shade, lick response window. c, % changes of HitIL, HitPL, Miss, FA, and CR rates by MUS injection compared with no injection (No inj.). d, % of HitPL trials across the trials with different levels of luminance. Dotted lines with squares, MUS injection; solid lines with circles, no injection controls. e, Same as d, but for HitIL trials. Color represents trial types. n.s. (not significant), *p < 0.05; two-sided Wilcoxon signed-rank test with Bonferroni correction for the statistics in c-e. Error bars show ± SEM. For detailed statistics information, see Supplementary Table 5.
