Extended Data Fig. 8: Correlation between licking response times (lick latency) and ramping activities of motor neurons in the ACC and the V1.
From: Gated feedforward inhibition in the frontal cortex releases goal-directed action
a, Fraction of MInc and MDec neurons that show ramp-to-threshold premotor activity in ACC and V1. Red and blue, neurons that show significant correlation between time to cross the lower threshold and lick latencies. b-d, Color-coded PSTHs (b), scatter plots (c), and ramp rates (d) of ACC MDec neurons that show significant correlation in a (neurons in the blue box) across trials with early-to-late lick latencies. Note that time to cross thresholds (either 1 or 8) in ramping-down activity of ACC MDec neurons showed a linear relationship with lick latency at a slope near 1, while ramping rates (the slopes of ramping-down activity) were constant. e-m, Same as Fig. 2l-n, but for ACC MInc (e-g), V1 MDec (h-j) and MInc neurons (k-m). For detailed statistics information, see Supplementary Table 5.
