Extended Data Fig. 8: Waveform measures. | Nature Neuroscience

Extended Data Fig. 8: Waveform measures.

From: Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex

Extended Data Fig. 8

Waveform measures and PCA with k-means clustering. a. Waveform measures on an example, spike waveform including the spike duration, halfwidth, peak-trough ratio, repolarization slope, recovery slope, and amplitude measures. b. Largest waveforms per unit showing positive polarity (grey) and negative polarity (black) waveforms across the data sets. c. Distribution of positive polarity (grey) and negative polarity (black) half-peak width and spike duration (peak-trough duration) of the largest waveform per unit (Pt. 01-03). d. The peak-trough ratio, repolarization slope, recovery slope of the channel with the largest waveform violin plots for the different clustered waveforms using the single channel and multichannel classifications. * indicate significant differences between all putative cell or waveform types, Kruskal-Wallis multiple comparison test, p < 0.001 with post hoc Tukey-Kramer test. Grey letters a-c indicate statistically separable groups. Left: single channel classifications. Middle: multichannel classification based on the principal components and k-means clustering across patients. Right: multichannel classification based on the WaveMAP clustering across patients.

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