Extended Data Fig. 4: Analysis of skull hematopoietic progenitors during meningitis. | Nature Neuroscience

Extended Data Fig. 4: Analysis of skull hematopoietic progenitors during meningitis.

From: Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis

Extended Data Fig. 4

a, Experimental outline for calvarial hematopoietic progenitor analysis. b, Flow cytometry gating. c, Quantitation of calvarial BrdU+ common myeloid progenitors (CMP) 6 hours after intracisternal sham or S. pneumococci injection. (n=11 sham and 12 meningitis, P value represents an unpaired, two-tailed t-test). d, Quantitation of calvarial BrdU+ CMP 24 hours after intracisternal sham or S. pneumococci injection. (n=6 mice per group, P value represents an unpaired, two-tailed t-test) e, Quantitation of calvarial BrdU+ LSK 24 hours after intracisternal sham or S. pneumococci injection. (n=6 mice per group, P value represents an unpaired, two-tailed t-test).

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