Extended Data Fig. 2: Distribution of tamoxifen-induced Cre activity in DAT-CreER mice and in TPH2-CreER mice.
From: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice
(a) Representative microscopic images with DAPI counter staining showing the presence or absence of tdTOMATO signals (red) in the VTA, SN, DRN and MRN in DAT-CreER/Rosa26-LSL-tdTOMATO mice. These imaging studies were repeated in 3 mice. (b) Representative microscopic images with DAPI counter staining showing the presence or absence of tdTOMATO signals (red) in the VTA, SN and DRN in TPH2-CreER/Rosa26-LSL-tdTOMATO mice. These imaging studies were repeated in 3 mice. Scale bars are indicated in each panel. DRN, dorsal Raphe nucleus; MRN, median Raphe nucleus; SN, substantia nigra; VTA, ventral tegmental area. Scale bars are indicated in each panel.
