Fig. 1: Profiling of genetically defined cortical pyramidal neuron classes. | Nature Neuroscience

Fig. 1: Profiling of genetically defined cortical pyramidal neuron classes.

From: Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex

Fig. 1

a, Schematic of experimental design. b, Representative coronal sections (n ≥ 3 biological replicates) showing correct laminar location of tdTomato+ cells in the somatosensory cortex and FACS plots of Tle4-CThPNs and Cux2-CPNs at P7. Scale bar, 100 μm. Also see Extended Data Fig. 1. c–e, Developmental dynamics of differentially expressed genes (c), differentially enriched ATAC-seq peaks (d) and DMRs (e). f, Fraction of dynamic features classified into each overall category. g, 2D MDS plots for each modality.

Back to article page