Extended Data Fig. 2: Mice fed HFD perform normally in the spontaneous sucrose consumption, EPM, and open field tests.
a, Representative tracings of chow and HFD mice performing the spontaneous sucrose consumption test in an open field apparatus. b-e, Quantification of the number of entries (b), the time spent (c), and the total distance (d) and speed (e) of travel per feeding zone during the sucrose consumption test for chow and HFD mice. n = 10 mice for each group. f, Bar graph showing the consumption of 10% and 30% sucrose during the test for chow and HFD mice. n = 10 mice for each group. g, Representative tracings of chow and HFD mice performing the EPM test. Open arms are horizontal in the panel. h, Quantification of the number of entries into the open arms (left) and the time spent in the open arms (right) for chow and HFD mice. n = 12 mice for each group. i, Representative tracings of control and HFD mice performing the open field test. j, Quantification of the number of central entries (left), the time spent in the central area (middle), and the total distance travelled (right) for control and HFD mice. n = 12 mice for each group. Data are mean ± SEM. See Supplementary Table 2 for further details of statistical data analysis.
