Fig. 2: MorphOMICs identifies sexually dimorphic microglial morphology in healthy adults. | Nature Neuroscience

Fig. 2: MorphOMICs identifies sexually dimorphic microglial morphology in healthy adults.

From: A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes

Fig. 2

a, Sagittal view of analyzed brain regions. b,c, MorphOMICs-analyzed microglia in male, female and ovariectomized adult mice. b, UMAP plot for each brain region color coded for males (left) or females (right) with dashed lines as reference. Each dot represents a bootstrapped persistence image. c, UMAP plot of ovariectomized females. Ovariectomized brain regions are highlighted. Gray indicates the non-ovariectomized counterpart as reference. nsamples = 500 per condition (‘Average and bootstrapped persistence images’).

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