Extended Data Fig. 9: BLA is required to develop altruistic preference.
From: Reciprocal cortico-amygdala connections regulate prosocial and selfish choices in mice
a, Latency to respond (in sec) grouped by altruistic and selfish choices in control (light and dark orange, n = 7) and hM4D mice (light and dark fuchsia, n = 7) during the five days of SDM task (two-way ANOVA, group (control, hM4D, altruistic, selfish), x time (days 1-5), F(12, 96)=2.39, p = 0.0093). b, Number of altruistic choices over 40 minutes of testing during the five days of the SDM in control and hM4D mice (mixed model analysis for each day of testing, day1: (control, hM4D) x time (min), F(16, 132)=0.48, p = 0.9915; day 2: group F(42, 267)=0.42, p = 0.9994; day 3: F(73, 685)=2.85, p < 0.0001; day 4: F(80, 716)=2.13, p < 0.0001; day 5: F(77, 696)=0.85, p = 0.8057). c, Decision preference score in the five days of SDM and following one additional week of testing (day 13) in control (n = 7) and hM4D (n = 7) mice (two-way RM ANOVA, group (control, hM4D) x time (days), F(5, 60)=2.875, p = 0.0416). d, Number of altruistic and selfish choices on test day 13 of the SDM in control (n = 7) and hM4D (n = 7) mice (two-way RM ANOVA, group (control, hM4D) x choice (altruistic, selfish), F(1, 12)=9.661, p = 0.0091). *p < 0.05, **p < 0.01, ***p < 0.001. Values are expressed as mean ± s.e.m.
