Extended Data Fig. 9: Task-related activity of ACC-DMS neurons.
From: A neural substrate of sex-dependent modulation of motivation
a. Trial-averaged, time-locked fluorescence to each task event for all imaged neurons. Neurons are sorted by the time of their peak fluorescence. b. Histograms showing the distribution of all imaged neurons, of the approximate numerical integral of the response kernel for the ‘no reward’ temporal kernel from the regression used to assess significant outcome encoding. The histograms are plotted separately for male and female neurons. The sign of the integral of the ‘no reward’ response kernel was used to classify neurons as reward-preferring (negative) or no reward-preferring (positive). c. Same as b for the ‘ipsilateral lever press’ event in the regression used to assess significant choice encoding. The sign of the integral was used to classify neurons as contra-preferring (negative) or ipsi-preferring (positive). d. Same as b for the ‘reward to stay’ event (left) and the ‘no reward to stay’ event (right) in the regression used to assess significant stay versus switch encoding. The sign of the integral was used to classify neurons as stay-preferring (positive) or switch-preferring (negative) for rewarded (left) and unrewarded (right) trials. n = 307 female neurons, 449 male neurons.
