Extended Data Fig. 3: Differential gene analysis across brain regions.
From: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease
a. Heatmap of the number of highly expressed brDEGs in each region and for each cell type. The intensity of the color corresponds to the quantity of brDEGs (indicated in each cell). b. Enriched Gene Ontology biological processes in each cell type. Heatmap of -log10(p-value) indicates the significance. Enrichr in R was used to perform GO enrichment (proportion test, adjusted p-value < 0.05 as cutoff, one-sided). Only regions with enriched terms were kept.
