Extended Data Fig. 4: Quantification of behaviors towards different intruders in Foxp2GCaMP and Dbx1GCaMP male mice, related to Fig. 3.
From: Transcriptionally defined amygdala subpopulations play distinct roles in innate social behaviors
(a) Percent of time naïve Foxp2GCaMP, socially experienced Foxp2GCaMP and socially experienced Dbx1GCaMP male mice spent investigating a male intruder. (b) The fraction of naïve Foxp2GCaMP, socially experienced Foxp2GCaMP and socially experienced Dbx1GCaMP male mice that attacked a male intruder. (c-e) Percent of time naïve Foxp2GCaMP, socially experienced Foxp2GCaMP and socially experienced Dbx1GCaMP male mice spent attacking a male intruder (c), as well as the latency to first attack (d) and total number of attack events (e). (f-l) Percent of time Foxp2GCaMP and Dbx1GCaMP male mice spent investigating (f), mounting (g), and intromitting (j) a receptive female intruder, as well as the total number of mounting events per recording session (h), latency to first mount (i), total number of intromission events (k) and latency to ejaculation (l). (m) Percent of time Foxp2GCaMP and Dbx1GCaMP male mice spent investigating a pup intruder. (a, c-m) Two-tailed unpaired t-tests (if pass normality test) or two-tailed Mann Whitney tests (if not pass normality test) between naïve Foxp2GCaMP and socially experienced Foxp2GCaMP animals, and between socially experienced Foxp2GCaMP and Dbx1GCaMP animals; (d) p = 0.0148, (f) p < 0.0001, (h) p = 0.0039 between naïve Foxp2GCaMP and socially experienced Foxp2GCaMP animals, (j) p = 0.0045 between naïve Foxp2GCaMP and socially experienced Foxp2GCaMP animals, (k) p = 0.0016 between naïve Foxp2GCaMP and socially experienced Foxp2GCaMP animals, (m) p = 0.0025 between socially experienced Foxp2GCaMP and socially experienced Dbx1GCaMP male mice. (b) Two-tailed Chi-square tests; p = 0.0023 between naïve Foxp2GCaMP and socially experienced Foxp2GCaMP animals. n = number of animals. Data are mean ± S.E.M.; *p < 0.05, **p < 0.01, ***p < 0.001. Otherwise, p > 0.05. See Source Data Extended Data Fig. 4 for more detailed statistics.
