Extended Data Fig. 3: Cluster MN4 corresponds to caudal MNs. | Nature Neuroscience

Extended Data Fig. 3: Cluster MN4 corresponds to caudal MNs.

From: Molecular blueprints for spinal circuit modules controlling locomotor speed in zebrafish

Extended Data Fig. 3

a, UMAP of log-normalized expression of the MN4 marker gene hoxb13a. b, Top: schematic of the analyzed rostrocaudal spinal cord regions. RNAscope in situ hybridization of hoxb13a in MNs in the rostral and caudal spinal cord regions. c, Box and whiskers plot of the number of punta in MNs along the rostral (R), middle (M) and caudal (C) spinal cord. MN4 marker gene hoxb13a is expressed in a rostrocaudal gradient in the spinal cord (the boxes are bound by the 25th and 75th percentiles, whiskers extend from min. to max.; R: n = 17; M: n = 21; C: n = 22 MNs from 3 animals; one-way ANOVA with Tukey’s post hoc multiple comparisons, **p = 0.0041, ****p < 0.0001).

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