Extended Data Fig. 9: Persistent activation of astrocytic somata but not surrounding gliapil for strong stimulation of locus coeruleus, extension of Fig. 7n. | Nature Neuroscience

Extended Data Fig. 9: Persistent activation of astrocytic somata but not surrounding gliapil for strong stimulation of locus coeruleus, extension of Fig. 7n.

From: Centripetal integration of past events in hippocampal astrocytes regulated by locus coeruleus

Extended Data Fig. 9

For these astrocytes, somata (blue) were activated shortly after gliapil (red) for weaker stimuli (10 s stimulation, 5 Hz, see Methods for details). For stronger stimulation (10 s stimulation, 20 Hz), somatic calcium signals were not simply a delayed version of gliapil signals but showed a persistent component. Such persistent activation was also observed without optogenetic stimulation during spontaneous behavior (Extended Data Fig. 7e,f).

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