Extended Data Fig. 4: BayesSpace clustering and reassignment to subgroups per WM sample.
From: Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis
Spatial plots depicting within-sample BayesSpace clustering in WM samples. Sample IDs are indicated on the upper left corner of each box, border colours correspond to the WM tissue group. Based on the BayesSpace clusters and cluster marker genes, spatial spots were reassigned into spatially distinct subgroups: lesion core (core, depicted in corresponding lesion colour), lesion rim (rim, depicted in black), perilesional white matter (PLWM, depicted in light grey) and grey matter (GM, depicted in dark grey). Clusters with low number of UMI counts and clusters representing GM areas in the WM tissues were excluded from downstream analyses.
