Extended Data Fig. 9: Sub-blocks within ModO are necessary to reproduce observed dynamics.

a. Comparison of estimated firing rates of identified integrator cells in larval zebrafish using calcium imaging (green) to firing rates simulated using a connectome-based model after shuffling the synapses within ModO (gray, see Methods). (left) Cumulative variance explained for the leading principal components of the average activity between two and six seconds after a saccade. Error bars about the mean show the standard deviation across 100 random shuffles of the network. (right) Best-fit amplitudes determined as in Fig. 5g. b, c. Same as a, but with ModO split into two sub-blocks (b) or seven sub-blocks (c) using a stochastic block model. Synapses were shuffled separately for each possible pairing of presynaptic block and postsynaptic block.