Extended Data Fig. 8: Geometric similarity of task representations across mazes for well-learned task.

The positions in principal component space for each maze are shown for both the Control (a) and GtACR2 (b) groups during each epoch of the well-learned task. For each epoch, gray lines represent Maze 1, while green lines correspond to Maze 2. The four dots on each line, which signify points P1, P2, P3, and P4, transition in color from light to dark in this order. Additionally, the marker size increases progressively from P1 to P4. P1 and P2 represent the common arms that share the same odor, while P3 and P4 correspond to the unique arms with distinct odors. c, Quantification of Procrustes analysis for the Control and GtACR2 groups in (a) and (b) was used to measure the geometric similarity between Maze 1 and Maze 2. No significant difference in geometric similarity between Maze 1 and Maze 2 was observed between the two groups across epochs (t₃₅ = 1.1, P = 0.28; two-tailed Student’s t-test; n = 36 for Control and GtACR2). Error bars are SEM.