Extended Data Fig. 9: Geometric similarity of task representations across mazes for learning of new task. | Nature Neuroscience

Extended Data Fig. 9: Geometric similarity of task representations across mazes for learning of new task.

From: Hippocampal output suppresses orbitofrontal cortex schema cell formation

Extended Data Fig. 9

Geometric similarity of task representations across mazes during new task learning. The positions in principal component space for each maze are shown for the Control (a) and GtACR2 groups (b) at each learning epoch. Gray lines represent Maze 1, and green lines represent Maze 2. In each epoch, four dots on each line, corresponding to positions P1, P2, P3, and P4, transition from light to dark, with marker sizes increasing progressively from P1 to P4. P1 and P2 represent the common arms, both sharing the same odor, while P3 and P4 correspond to the unique arms, each with distinct odors. c, Procrustes analysis was performed for the Control and GtACR2 groups in (a) and (b) to evaluate the geometric similarity between Maze 1 and Maze 2. Across epochs, no significant differences in geometric similarity between the two mazes were observed between the groups (t35 = 4.4, P = 1.1 × 10−4; two-tailed Student’s t-test; n = 36 for Control and GtACR2). Error bars are SEM.

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