Fig. 1: Neuropixels 1.0 NHP probe characterization and engineering.
From: Large-scale high-density brain-wide neural recording in nonhuman primates
a, Comparison of probe geometry with macaque brain and the Neuropixels 1.0 probe. b, Recording site layout. c, Some 4,416 recording sites covering the full length of the shank, grouped in 11.5 banks of 384 channels. Ch., channel. d, Neuropixels 1.0 NHP probe silicon die photograph, indicating the four segments or sub-blocks used for the subfield stitching fabrication process. e, Details of the shank tip reference electrode layout (top) and CMOS circuit layout (bottom). The different shapes and colors represent the CMOS process layers used in the layout. f, SEM image of one of the metal layers in the shank when crossing the stitching region. Scale bar, 1 µm. Top left, cross-section taken outside the stitching overlap region. Top right, cross-section at the narrowest point. The metal wires are narrower as a result of the double resist exposure. Inset scale bar units in nanometers. g, SEM image of shank tip mechanically ground out of plane to 25°. Inset, probe-tip geometry as fabricated, pre-grinding. h, Raw electrical recordings from 384 simultaneous channels in the motor cortex of a rhesus macaque monkey. Insets, expanded view of single spike events from single neurons. i, Example waveforms from isolated single neurons (gray) and median waveform (colored). j, Auto- and CCGs for neurons shown in i.
