Extended Data Fig. 2: Cell state characterization in the GABAergic lineage. | Nature Neuroscience

Extended Data Fig. 2: Cell state characterization in the GABAergic lineage.

From: Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice

Extended Data Fig. 2

a, Heatmap of top five differentially expressed genes in GABAergic cell clusters. b, UMAP plot of combined datasets with cells colored by cluster identity. Clusters are annotated by one or two top marker genes. c, UMAP plot of combined datasets with inferred Monocle 3 trajectory. Cells are colored by pseudotime. d, Expression of marker genes in the combined dataset. Nes and Fabp7 label APs, Ascl1 and Ccnd2 are markers for BPs. Post-mitotic inhibitory neurons express Gad2 and Dlx6os1. Meis2 labels PNs and Tcf4 labels INs. e, UMAP plot of combined datasets, with cells colored by broad cell states. f, UMAP plot of combined datasets colored by cell cycle phases.

Source data

Back to article page