Extended Data Fig. 4: Shared molecular signatures of immature neurons in the hippocampus of different species. | Nature Neuroscience

Extended Data Fig. 4: Shared molecular signatures of immature neurons in the hippocampus of different species.

From: Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes

Extended Data Fig. 4

a, GO network of biological processes associated with imGC-enriched genes in different species in comparison to mGCs, colored by FDR-adjusted P value. Only significantly enriched nodes are displayed (one-sided hypergeometric test, FDR-adjusted P < 0.05). The node size represents the term enrichment significance. Examples of the most substantial terms per group are shown. b, Violin plots showing normalized expression of 8 imGC-enriched genes shared across four species in imGCs and GCs (one-way Wilcoxon rank-sum test). A total of nine shared genes were identified and eight are shown here (see Fig. 3d for the plot for the ninth gene, DPYSL5). Schematics created using BioRender.com.

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