Extended Data Fig. 2: Individual VEI activated their target neuron strongly.
From: Functional bipartite invariance in mouse primary visual cortex receptive fields
a, For each neuron, we randomly selected ten VEIs (red) from the set of 20 VEIs. Individual VEIs stimulated in vivo closely to the level predicted in silico with respect to MEI (72 ± 4% versus 85%) (two-sided Wilcoxon signed-rank test, W = 519434, P = 0.03), with only 274 out of all 1490 individual VEIs (18.4%) evoked responses lower than 85% of the corresponding MEI (3.0% after BH correction; P < 0.05, one-sided Welch’s t-test with 32.5 average d.f.). b, Fraction of correctly rejected null hypotheses as a function of response reduction from the 85% threshold; the shaded region indicates the 95% confidence interval. c,d, To quantify the in vivo response relationship between MEI and VEIs, we performed bootstrapping by either averaging across 20 randomly selected trials from a single VEI (c) or 20 randomly selected trials from 10 different VEIs (d) (Methods). e, The linear coefficients estimated using individual VEI (c, median=0.71) were similar to those estimated using multiple VEIs (d, median=0.76) (P = 0.59, two-sided bootstrapped mean difference against 0). Data were pooled over 149 neurons from two mice.
