Supplementary Figure 8: Econazole flexibility during MD production run
From: Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
a Time evolution of the RMSD of R-econazole (labeled ECN_1 to ECN_4) with respect to the initial manual docking into the assigned electron density within the four monomers of TRPV5 (monomers A to D, respectively) during the 25 ns production run. b Time evolution of the RMSD of S-econazole (labeled ECN_1 to ECN_4) with respect to the initial manual docking into the assigned electron density within the four monomers of TRPV5 (monomers A to D, respectively) during the 25 ns production run.
