Supplementary Figure 4: Mapping external information for residue-level analysis of structures
From: Visualization and analysis of non-covalent contacts using the Protein Contacts Atlas
a, Scatter plot of residues in the G protein after mapping their stability data (experimentally inferred binding affinity) using a color spectrum (min: cyan; max: magenta). Stability was measured as ΔTm = Tm of Gαi1(Ala) - Tm of Gαi1(WT) with 1mM GDP. Residue F336G.H5.8 is shown in red and the rest of the residues in cyan and magenta according to their ΔTm values. b, Network view and asteroid plot of F336G.H5.8 shows the extensive nature of the contacts this residue mediates in the GDP bound structure of Gαi1 (1GDD).
