Supplementary Figure 1: Chemical structures of tunicamycin and the natural substrates of GPT and MraY. | Nature Structural & Molecular Biology

Supplementary Figure 1: Chemical structures of tunicamycin and the natural substrates of GPT and MraY.

From: GlcNAc-1-P-transferase–tunicamycin complex structure reveals basis for inhibition of N-glycosylation

Supplementary Figure 1

Chemical structure of the competitive inhibitor tunicamycin A1 is shown at the top, while the structures of the natural substrates (UDP-GlcNAc for GPT and UDP-MurNAc-pentapeptide for MraY) are shown at the bottom. All compounds contain uridine moieties and either a GlcNAc or MurNAc moiety.

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